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Pyruvate Kinase Deficiency

Pyruvate Kinase Deficiency (PKDef, not to be confused with PKD). Cats may have a single copy of the PKDef mutation, these cats are clinically normal and are termed heterozygous or carriers, but they can pass the mutation to their offspring. Cats with two copies of the PKDef mutation are termed homozygous affected and are likely to suffer from episodes of anaemia.

Langfords Veterinary Services

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